{"id":132421,"date":"2019-03-01T15:53:19","date_gmt":"2019-03-01T13:53:19","guid":{"rendered":"http:\/\/www.myza.co.za\/keyhole-in-utero-blood-transfusion-procedure-saves-durban-baby-baby-mihle-discharged-from-netcare-st-augustines-hospital\/"},"modified":"2019-03-01T15:53:19","modified_gmt":"2019-03-01T13:53:19","slug":"keyhole-in-utero-blood-transfusion-procedure-saves-durban-baby-baby-mihle-discharged-from-netcare-st-augustines-hospital","status":"publish","type":"post","link":"https:\/\/www.myza.co.za\/press\/keyhole-in-utero-blood-transfusion-procedure-saves-durban-baby-baby-mihle-discharged-from-netcare-st-augustines-hospital\/","title":{"rendered":"Keyhole in-utero blood transfusion procedure saves Durban baby -Baby Mihle discharged from Netcare St Augustine\u2019s Hospital"},"content":{"rendered":"<p><a target=\"_blank\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" href=\"http:\/\/mypr.co.za\/keyhole-in-utero-blood-transfusion-procedure-saves-durban-baby-baby-mihle-discharged-from-netcare-st-augustines-hospital\/\">Keyhole in-utero blood transfusion procedure saves Durban baby -Baby Mihle discharged from Netcare St Augustine\u2019s Hospital<\/a>: <\/p>\n<div id=\"attachment_69337\" style=\"width: 750px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-69337\" class=\"wp-image-69337 size-large\" src=\"http:\/\/mypr.co.za\/wp-content\/uploads\/2019\/03\/Baby-Biyela-pic-1-copy-1000x870.jpg\" alt=\"\" width=\"740\" height=\"644\" srcset=\"http:\/\/mypr.co.za\/wp-content\/uploads\/2019\/03\/Baby-Biyela-pic-1-copy-1000x870.jpg 1000w, http:\/\/mypr.co.za\/wp-content\/uploads\/2019\/03\/Baby-Biyela-pic-1-copy-400x348.jpg 400w, http:\/\/mypr.co.za\/wp-content\/uploads\/2019\/03\/Baby-Biyela-pic-1-copy-768x668.jpg 768w, http:\/\/mypr.co.za\/wp-content\/uploads\/2019\/03\/Baby-Biyela-pic-1-copy-500x435.jpg 500w\" sizes=\"auto, (max-width: 740px) 100vw, 740px\" \/><\/p>\n<p id=\"caption-attachment-69337\" class=\"wp-caption-text\">Ready to go home: Baby Mihle with his parents Mr Phiwayinkosi Biyela (right), Mrs Ntombenhle Biyela and foetal specialist Dr Ismail Bhorat, who performed the in-utero keyhole blood transfusion procedure, before his discharge from Netcare St Augustine\u2019s Hospital.<\/p>\n<\/div>\n<p>Saved from a life-threating condition by an advanced in-utero keyhole blood transfusion procedure at 25 weeks while still in his mother\u2019s womb, baby Mihle Biyela\u2019s parents were overjoyed last week to take their healthy and bouncing son home from Netcare St Augustine\u2019s Hospital in Durban, where he was born on 12 February this year.<\/p>\n<p>Mihle\u2019s parents, Mr Phiwayinkosi Biyela and Mrs Ntombenhle Biyela, say that they regard their little boy as a \u201cmiracle baby\u201d, as they had been warned that the foetus suffered from a life-threatening condition known as hydrops fetalis, which was characterised by a fluid build-up around the heart, lungs and other locations, and was unlikely to survive.<\/p>\n<p>Fortunately, Mrs Biyela sought a second opinion from gynaecologist and obstetrician, Dr Bongani Mazibuko who practises at Netcare St Augustine\u2019s Hospital, after it was recommended that her pregnancy be terminated. Dr Mazibuko in turn contacted foetal specialist, Dr Ismael Bhorat, KwaZulu-Natal\u2019s only foetal specialist in private practice, for assistance and they commenced investigations into what was causing the condition. The diagnosis of the foetal anaemia was made using advanced sonographic and Doppler techniques investigating the peak flow velocity in an artery in the brain.<\/p>\n<p>\u201cHydrops fetalis can be caused by a variety of different underlying conditions, which can result in a myriad of potential complications. The prognosis for the foetus is dependent on establishing the exact cause and then treating it early and appropriately. Without this, the condition is almost invariably fatal for the foetus,\u201d says Dr Bhorat.<\/p>\n<p>Dr Bhorat, who practises at Netcare uMhlanga Hospital, led the team who performed a life-saving in-utero keyhole blood transfusion procedure called an IUT (intrauterine blood transfusion), when the foetus was only 25 weeks.<\/p>\n<p>Grateful for their little survivor, the Biyela family decided to name the baby \u201cMihle Imisebenzi kaNkulunkulu\u201d, which translates from Zulu as \u201cBeautiful work of God\u201d. \u201cIt has been a difficult and painful journey with Mihle, as we were originally warned that he had very little chance of surviving,\u201d said Mrs Biyela. \u201cThrough the mercy of God and thanks to the wonderful care of the doctors and nurses, we were overjoyed to be taking Mihle home.<\/p>\n<p>\u201cI can\u2019t wait to spend more time with him, as a mom needs to bond with her son,\u201d added the mother of two, who originally hails from Nkandla in northern KwaZulu-Natal, and now lives in Durban.<\/p>\n<p>Dr Bhorat adds: \u201cWhat baby Mihle\u2019s case highlights, is that with accurate diagnosis and early and appropriate specialised intervention, there is hope for many hydrops babies and they can often be saved. The proper identification of the cause or causes of the condition is critical, however, as these have to be addressed in order to have a chance of resolving the hydrops fluid build up.<\/p>\n<p>\u201cWe are absolutely delighted to have been able to save baby Mihle\u2019s life, who was suffering heart failure due to severe anaemia since the heart had to pump harder to get blood to the cells and the heart eventually failed.<\/p>\n<p>\u201cWe established that the hydrops was not as a result of immune system problems, but was likely caused by a viral infection that had attacked the foetus\u2019 red blood cells, resulting in severe foetal anaemia. Under such circumstances the in-utero blood transfusion procedure is indicated. Before performing the procedure 1-2 ml of foetal blood is extracted, in a procedure called a cordocentesis, to determine the haemoglobin level of the foetus.\u201d<\/p>\n<p>\u201cThis information is needed to determine the exact volume of blood to be transfused. The foetus immediately started to recover after just a single IUT procedure, and suffered no further complications as a result of the hydrops, and continued to develop strongly. Working closely with Dr Mazibuko, we were then able to get baby Mihle to a healthy 36 weeks when he could be safely delivered.\u201d<\/p>\n<p>Dr Bhorat says that the minimally invasive IUT procedure is well described, but is only indicated in rare cases such as this. Hydrops can so easily result in complications, and has a mortality rate of some 90%, and the procedure itself is intricate, requiring blood to be carefully replaced in the correct volume.<\/p>\n<p>A needle has to be guided through ultrasound control into the umbilical cord so that the blood can be sampled for testing, and the blood transfusion can then be undertaken. Complications that can occur are slowing of the heart rate, leakage of blood from the insertion site or clot (haematoma) formation in the cord.<\/p>\n<p>\u201cWe managed to obtain the necessary O-negative irradiated blood within two days. Often a number of blood transfusions are necessary before the hydrops begins to resolve but in this case the foetus responded after a single transfusion.\u201d<\/p>\n<p>Dr Bhorat says that the haemoglobin of the foetus was determined to be 3g\/dl which is extremely low and explains the cardiac failure (normal foetal haemoglobin is 15-16g\/dl).<\/p>\n<p>\u201cThe team is delighted that we got every aspect of the condition and treatment accurate and correct, and that it was such a success. When I saw baby Mihle for the first time after birth, it brought tears to my eyes.\u201d<\/p>\n<p>\u201cWe would like to convey our appreciation to our families, colleagues, friends, and brothers and sisters of our church, \u2018The House Of The Twelve Apostles, for their support and prayers through our experience with Mihle,\u201c said Mr Biyela.<\/p>\n<p>\u201cMy family and I are also most grateful to Dr Bhorat, Dr Mazibuko and their teams at both Netcare St Augustine\u2019s and Netcare uMhlanga hospitals. They kept us informed and reassured us every step of the way through the treatment and the pregnancy. From thinking that I was sure to lose my baby, to being able to take Mihle home, is the greatest gift I have ever been given,\u201d added Mrs Biyela.<\/p>\n<p>Netcare St Augustine\u2019s general manager, Heinrich Venter, says that the staff and management of the facility were all deeply moved by baby Mihle\u2019s case and celebrated that he could go safely home last Thursday.<\/p>\n<p>\u201cWe are delighted at the positive outcome and to have played a role in baby Mihle\u2019s care. 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