{"id":227130,"date":"2022-05-25T23:36:15","date_gmt":"2022-05-25T21:36:15","guid":{"rendered":"https:\/\/www.myza.co.za\/artificial-light-may-become-a-new-weapon-in-the-fight-to-control-malaria\/"},"modified":"2022-05-25T23:36:15","modified_gmt":"2022-05-25T21:36:15","slug":"artificial-light-may-become-a-new-weapon-in-the-fight-to-control-malaria","status":"publish","type":"post","link":"https:\/\/www.myza.co.za\/press\/artificial-light-may-become-a-new-weapon-in-the-fight-to-control-malaria\/","title":{"rendered":"Artificial light may become a new weapon in the fight to control malaria"},"content":{"rendered":"<div><img decoding=\"async\" src=\"http:\/\/www.myza.co.za\/press\/wp-content\/uploads\/2022\/05\/artificial-light-may-become-a-new-weapon-in-the-fight-to-control-malaria.jpg\" class=\"ff-og-image-inserted\"><\/div>\n<p>The world has not yet won the war against malaria. While the total number of cases has declined from about 81.1 cases per 1,000 population to 59 per 1,000 since 2000, there were still an estimated <a href=\"https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2021\">240 million cases and 600,000 deaths<\/a> in 2020 globally. <\/p>\n<p>Malaria remains a menace across Africa. The continent carries by far the world\u2019s <a href=\"https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2021\">largest disease burden<\/a>: 94% of cases and 96% of deaths occur across the continent. Alarmingly, children aged five or younger account for <a href=\"https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2021\">80% of these deaths<\/a>.<\/p>\n<p>There is no room for complacency. While <a href=\"https:\/\/www.who.int\/news\/item\/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk\">vaccines look promising<\/a>, there is still a steady rise of antimalarial drug resistance, especially in East Africa. The <a href=\"https:\/\/theconversation.com\/some-malaria-parasites-are-evading-detection-tests-causing-an-urgent-threat-to-public-health-177258\">parasites are evolving<\/a> mutations which allow them to escape routine diagnosis. The mosquitoes are also evolving increased <a href=\"https:\/\/theconversation.com\/fresh-signs-of-mosquito-insecticide-resistance-in-south-africa-181618\">resistance to insecticides<\/a>.<\/p>\n<hr>\n<p> <em> <strong> Read more: <a href=\"https:\/\/theconversation.com\/malaria-elimination-in-southern-africa-possibly-but-these-gaps-need-attention-171031\">Malaria elimination in southern Africa? Possibly, but these gaps need attention<\/a> <\/strong> <\/em>\n<\/p>\n<hr>\n<p>This situation underscores the need for sharpening the multiple vector control options, and exploring new strategies. <\/p>\n<p><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fevo.2021.768090\/full\">My research<\/a> explores one such potential strategy: the use of artificial lights to trick malaria-transmitting mosquito species that feed nocturnally into behaving as if it\u2019s daytime. This may deter feeding, helping to keep people safe from malaria-carrying mosquito bites. <\/p>\n<h2>New light<\/h2>\n<p>Light is a fundamental cue in nature. It regulates much of the timing of biological events, like when birds breed, lions hunt \u2013 and humans\u2019 sleep patterns. It is also an ancient cue. While species have been exposed to changes in climate cycles over the eons, the timing of day and night has remained relatively constant over evolutionary time, owing to the rotation of the earth. This means that all life on the planet has evolved with such regular day-night cycles. The gene for the <a href=\"https:\/\/www.nccih.nih.gov\/health\/melatonin-what-you-need-to-know\">melatonin hormone<\/a>, which regulates sleep-awake cycles, is shared between widely different and old taxonomic groups, such as plants and animals.<\/p>\n<p>However, these natural dark cycles are <a href=\"https:\/\/theconversation.com\/skyglow-forces-dung-beetles-in-the-city-to-abandon-the-milky-way-as-their-compass-165110\">rapidly changing<\/a> because people are increasingly using artificial light. <a href=\"https:\/\/www.darksky.org\/80-of-world-population-lives-under-skyglow-new-study-finds\/\">Nearly 80%<\/a> of the world\u2019s people now live under artificially lit skies. <\/p>\n<p>So, what impact might such artificial light use have on malaria? <\/p>\n<h2>Altering mosquito biology<\/h2>\n<p>The <em>Anopheles<\/em> group of mosquitoes, which is responsible for all of Africa\u2019s malaria cases, is a nocturnal feeder. After mating, the females will seek out a blood meal. In doing so, they transfer the <em>Plasmodium<\/em> parasite which causes malaria. This is why bed nets are <a href=\"https:\/\/www.thelancet.com\/journals\/langlo\/article\/PIIS2214-109X(21)00216-3\/fulltext\">so effective<\/a> when used correctly \u2013 they block bites when people are sleeping at night.<\/p>\n<hr>\n<p> <em> <strong> Read more: <a href=\"https:\/\/theconversation.com\/curious-kids-what-would-happen-if-all-the-mosquitoes-in-the-world-disappeared-175528\">Curious Kids: What would happen if all the mosquitoes in the world disappeared?<\/a> <\/strong> <\/em>\n<\/p>\n<hr>\n<p><a href=\"https:\/\/parasitesandvectors.biomedcentral.com\/articles\/10.1186\/s13071-017-2196-3\">Emerging research<\/a>, including <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fevo.2021.768090\/full\">my own<\/a>, <a href=\"https:\/\/www.researchgate.net\/publication\/348313670_Artificial_light_and_biting_flies_the_parallel_development_of_attractive_light_traps_and_unattractive_domestic_lights\">argues<\/a> how artificial light at night can change mosquitoes\u2019 behaviour.<\/p>\n<p>This is because the artificial light used in homes can alter mosquito biology. For example, a short pulse of Light Emitting Diode (LED) light, commonly used lights in homes as \u201cdownlights\u201d or reading lamps, can delay the onset of biting by hours in <em>Anopheles<\/em>, and so reduce biting rates and malaria transfer. The light essentially tricks the mosquitoes into not feeding.<\/p>\n<p>These ideas are promising. But strategies to control vectors don\u2019t always work at a bigger scale, especially if those strategies are not properly applied. For instance, bed nets treated with mosquito repellents are sometimes <a href=\"https:\/\/theconversation.com\/mosquito-nets-are-often-used-for-fishing-a-smart-response-is-needed-66283\">used as fishing nets<\/a> in parts of Africa. Demonstrating the effects of artificial light in controlled laboratory settings is one thing, but rolling out their use as an effective vector control strategy is quite another.<\/p>\n<p>Even if governments could easily get LED lights into many homes to guard against malaria-carrying mosquitoes, there might be unintended consequences for human health. A burgeoning <a href=\"https:\/\/www.ama-assn.org\/sites\/ama-assn.org\/files\/corp\/media-browser\/public\/about-ama\/councils\/Council%20Reports\/council-on-science-public-health\/a16-csaph2.pdf\">body of research<\/a> is examining the effects of artificial light on human health. Early indications are that it can have negative impacts like disrupted sleep.<\/p>\n<h2>A growing body of research<\/h2>\n<p>Overall, it is not yet clear how artificial lights might be used to lessen the risk of malaria infections. But the growing body of work on this issue suggests that it\u2019s a concept which needs more attention from the World Health Organization and other groups.<\/p>\n<p>Once the impacts of artificial light use are more fully understood, developmental planners across Africa might be able to ensure that lights of the correct kinds, used in optimal places and times, become part of the continent\u2019s efforts to control malaria.<\/p>\n<p> <a href=\"https:\/\/theconversation.com\/africa\/\">Source: The Conversation<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The world has not yet won the war against malaria. While the total number of cases has declined from about 81.1 cases per 1,000 population to 59 per 1,000 since 2000, there were still an estimated 240 million cases and 600,000 deaths in 2020 globally. Malaria remains a menace across Africa. The continent carries by [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":227131,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","ngg_post_thumbnail":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[4584],"tags":[3257],"class_list":{"0":"post-227130","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-africa-news-2","8":"tag-mypr","9":"entry"},"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/www.myza.co.za\/press\/wp-content\/uploads\/2022\/05\/artificial-light-may-become-a-new-weapon-in-the-fight-to-control-malaria.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/posts\/227130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/comments?post=227130"}],"version-history":[{"count":0,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/posts\/227130\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/media\/227131"}],"wp:attachment":[{"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/media?parent=227130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/categories?post=227130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.myza.co.za\/press\/wp-json\/wp\/v2\/tags?post=227130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}